Topic outline

  • General

    Introduction to protein structure visualization and comparison using Swiss-PdbViewer

    Lausanne, 7 November 2013

    Course description:

    This course is aimed at biologists who wish to get acquainted with protein structure visualization.
    After a short introduction on protein structure, the whole course will be centered around the practical utilization of Swiss-PdbViewer.

    In particular, you will learn how to
    - look at a structure, both globally (as a fold) or in detail (e.g. an active site)
    - compare several structures to identify differences
    - identify residues participating in protein-protein interactions
    - understand the limits of energy minimization
    - make a crude model to visualize the result of genetic mutations onto a protein structure.

    To maximize the learning experience, the course is structured as a practical demonstration that students can follow repeating the same operation on their own laptop.
    At the end of the course, the students will be presented with a few questions that they will have to answer using their newly acquired structural knowledge.

    Requirements:

    Basic knowledge of biology (DNA, protein sequence) is required to attend the course.
    Bring a laptop wifi enabled with a working installation of SwissPdbViewer (http://spdbv.vital-it.ch/).
    To verify that the application is compatible with your hardware / graphic card, unzip the package and drag the 1crn.ent file onto the Swiss-PdbViewer application. A structure should appear in the main window.
    Known incompatible hardware: Windows 8 running on SurfacePro.

    Registration:

    Registration is closed.

    The registration fees for academics are 50 CHF. The fees include course content material and coffee breaks. Participants from non-academic institutions should contact us.

    You are welcome to register to the SIB courses mailing-list to be informed of all future courses and workshops, as well as all important deadlines using the form here.
    For more information, please contact education@isb-sib.ch