Topic outline

  • Enrichment analysis

    Lausanne, 11 March 2019

    University of Lausanne, Amphipôle building, room 202

    This page is addressed to registered participants. To access course description and application form, please click here.

    For any assistance, please contact training@sib.swiss.

  • R packages to install PRIOR TO the course

    library("clusterProfiler") 
    library("AnnotationDbi")
    library("rat2302.db")
    library(“DescTools”)
    library(org.Hs.eg.db)
    library(org.Rn.eg.db)

  • Schedule

    9:00  - 10:30    

    Recall:

    a. Differential expression

    b. Statistical tests

    Exercise

    10:30  - 10:45    coffee break

    10:45  - 12:30    

    Threshold-based versus Threshold-free enrichment

    GSEA advantages and drawbacks

    Classification of available gene enrichment methods

    Exercise

    12:30  - 13:30  lunch (on your own)

    13:30  - 15:30   

    Generalizing enrichment

    Exercice

    15:30  - 15:45  coffee break

    15:45  - 17:00  

    Ontologies and enrichment

    Exercise

    17:00    end of day